It is our experience that an expert opinion is important for delivering an in depth assessment of the compounds.
- Part of the expert opinion is to investigate the system generated analogues and if needed run the compounds in multiple models to obtain the holistic picture.
- When the QSAR models system calls out – positive or in-conclusive predictions, it is of key importance to establish an expert opinion. Moreover, when a prediction, is a combination of an “out of domain” call and a “negative” prediction, the expert report must be strong.